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European Lead Factory successfully creates ‘drug-like’ hit compounds
Just a few months after its inclusion for drug target screening, one of the first compounds synthesised within the European Lead Factory was identified as a ‘drug-like’ hit. The compounds were synthesised by the Public Chemistry Consortium, based on library proposals from academic groups and small- and medium-sized enterprises (SMEs) in Europe.
Press Release: ELF wins award and delivers 50,000 new compounds
Knowledge-sharing at the PostDoc Learnings and Achievements meeting
Knowledge-sharing and education are key features of the European Lead Factory. Twice a year, chemistry PostDocs from within the consortium get the opportunity to present their research at the PostDoc Learnings and Achievements meeting.
Stefan Jaroch introduced as new Project Coordinator
During the European Lead Factory General Assembly meeting held on 26-27 March 2015 in Germany/Dortmund, Stefan Jaroch was introduced as the new project coordinator.
ELF awards screening programme to CELLIPSE
CELLIPSE was awarded an exclusive High Throughput Screening research program to screen the EU Lead Factory’s (ELF) joint compound library on an undisclosed innovative therapeutic target, by the Selection Committee on January 19 2015.
NTRC receives qualified hit series for TDO from the European Lead Factory
NTRC, a biotech company based at Pivot Park in Oss, The Netherlands, is the first SME ever to receive a Qualified Hit List from the European Lead Factory that was generated using NTRC’s NFK GreenScreen™ assay technology.
Business Leadership Award for Professor Andrew Hopkins
January 2015 Newsletter now available!
Topics in this issue: 1st publication on the character of the Joint European Compound Library - Crystal structures of QHL compounds with target -1stSME to receive a Qualified Hit List! -ELF Meeting: Chemistry Postdoc Learnings and Achievements -Meet the ELFs -Almost 40,000 JECL compounds synthesised - Status of JECL and Target Programmes
Our partner EDELRIS is celebrating 10 000 molecules prepared for the European Lead Factory project!
The European Screening Centre now also supports target assays with Ca2+ readout
The European Screening Centre now also supports target assays with Ca2+ readout. Using an integrated FLIPR Tetra fully equipped with ICCD-camera, TetraCycler and heads ranging from 96 to 1536-well format, a wide range of real-time calcium kinetics and ion channel assays can be applied.
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